Herregods P, Willems J, Chappel R
Dept of Physical Medicine and Rehabilitation, Middleheim Hospital, Antwerp, Belgium.
Clin Rheumatol. 1997 Jun;16(4):425-8. doi: 10.1007/BF02242464.
The authors describe a 12-year old girl with a painful syndrome at the distal side of the left leg, resulting in limping, incapacity and severe muscle atrophy. Full investigation - no inflammatory laboratory signs, diffuse osteoporosis at the left leg, decreased bone mineral content at the same place, marked hypofixation on bone and vascular scintigraphy - suggested pseudodystrophy (5), which is often induced by psychological factors. Successful treatment was obtained by physiotherapy, hydrotherapy, slight doses of NSAID and psychological assistance. With regard to recent literature, the authors believe that reflex sympathetic dystrophy (RSD) in children is often over-diagnosed, since there are no recognised criteria for diagnosing RSD. Besides the clinical picture, changes on radiography (focal osteoporosis) and on scintigraphy (disturbed vascular scintigraphy with increased pooling in the initial phase and hyperfixation on bone scintigraphy) are necessary. When these are not available, pseudodystrophy is a more correct diagnosis.
作者描述了一名12岁女孩,其左腿远端出现疼痛综合征,导致跛行、功能丧失和严重肌肉萎缩。全面检查——无炎症实验室指标,左腿弥漫性骨质疏松,同一部位骨矿物质含量降低,骨与血管闪烁扫描显示明显固定减低——提示为假性营养不良(5),其常由心理因素诱发。通过物理治疗、水疗、小剂量非甾体抗炎药及心理辅助获得了成功治疗。关于近期文献,作者认为儿童反射性交感神经营养不良(RSD)常被过度诊断,因为尚无公认的RSD诊断标准。除临床表现外,放射学改变(局灶性骨质疏松)和闪烁扫描改变(血管闪烁扫描异常,初始阶段有造影剂聚集增加,骨闪烁扫描有过度固定)也是必要的。若无法获得这些表现,则假性营养不良是更正确的诊断。