DNA修复：RAD警报。
DNA repair: RAD alert.
作者信息
Ivanov E L, Haber J E
机构信息
Transkaryotic Therapies Inc, Cambridge, Massachusetts 02139, USA.
出版信息
Curr Biol. 1997 Aug 1;7(8):R492-5. doi: 10.1016/s0960-9822(06)00246-6.
PMID:9259545
Abstract
Mammalian homologues of two important yeast genes involved in DNA double-strand break repair and recombination, RAD51 and RAD54, have been isolated. Knock-out mutations of the genes in mice reveal both reassuring similarities to, and surprising differences from, the analogous mutant phenotypes in yeast.
摘要
参与DNA双链断裂修复和重组的两个重要酵母基因RAD51和RAD54的哺乳动物同源物已被分离出来。小鼠中这些基因的敲除突变显示出与酵母中类似突变表型既有令人安心的相似之处，也有惊人的差异。
Zotero 插件