Storrie-Baker H J, Segalowitz S J, Black S E, McLean J A, Sullivan N
Department of Psychology, West Park Hospital, Toronto, Ontario, Canada.
J Int Neuropsychol Soc. 1997 Jul;3(4):394-402.
Introducing ice-water into the left ear of right-brain-damaged patients attenuates unilateral neglect symptoms. By examining EEG changes over each hemisphere during this procedure, we were able to test a hypothesis concerning the mechanism of cold-water calorics and the attention-arousal hypothesis of hemispatial neglect. We present a case study of an 83-year-old woman with a massive right-hemisphere CVA exhibiting severe hemispatial neglect. Caloric stimulation produced a leftward eye deviation to central position, and a temporary partial remission of neglect symptoms. Significant changes in EEG activation indicated a central mechanism associated with the regularization of eye gaze. Caloric stimulation also produced a significant interaction between EEG frequency band and hemisphere, indicating that while both hemispheres increased in cortical activation, the right hemisphere increase was significantly greater. This supports the activation-arousal hypothesis of neglect over the mutual inhibition model.
将冰水引入右脑损伤患者的左耳可减轻单侧忽视症状。通过在此过程中检查每个半球的脑电图变化，我们能够检验一个关于冷水热量刺激机制和半侧空间忽视的注意力唤起假说的假设。我们报告一例83岁女性，因右侧大脑半球大面积脑卒中有严重半侧空间忽视症状。热量刺激使眼球向左偏至中央位置，且忽视症状暂时部分缓解。脑电图激活的显著变化表明存在与眼球注视正常化相关的中枢机制。热量刺激还在脑电图频段和半球之间产生了显著的交互作用，表明虽然两个半球的皮质激活均增加，但右半球的增加更为显著。这支持了忽视的激活唤起假说而非相互抑制模型。
