Bertrand L
J R Coll Physicians Lond. 1977 Oct;12(1):30-5.
Acute alcoholic hepatitis is an anatomical (fatty liver with sclerosing hyaline necrosis) and a clinical (hepatomegaly with a variety of symptoms of hepatic failure) entity arising out of chronic alcoholism, and of a typically 'pre-cirrhotic' state. Although fatal in 25% of acute cases due to failure of homeostasis, it often leaves a centrilobular scarring necrosis which in more than 60% of cases progresses to nodular cirrhosis. Continued alcoholism worsens the prognosis. Alcoholic hepatitis may be confused with acute abdominal catastrophes or with a hepatoma. The characteristic Mallory bodies found on liver biopsy are found rarely in non-alcoholic hepatitis. There is no effective treatment for this disease except reduction of alcohol intake; indeed, the disease may become self-perpetuating.
急性酒精性肝炎是一种由慢性酒精中毒引起的解剖学（伴有硬化性透明坏死的脂肪肝）和临床（肝肿大伴各种肝功能衰竭症状）实体，处于典型的“肝硬化前期”状态。尽管25%的急性病例因内稳态失衡而致命，但它通常会留下小叶中心瘢痕性坏死，其中超过60%的病例会发展为结节性肝硬化。持续酗酒会使预后恶化。酒精性肝炎可能与急性腹部急症或肝癌相混淆。肝活检发现的特征性马洛里小体在非酒精性肝炎中很少见。除了减少酒精摄入外，这种疾病没有有效的治疗方法；事实上，这种疾病可能会自我延续。
