Bour B, Person B, Calès P, Blanchi A, Burtin P, Oberti F, Boyer J, Kaassis M, Joundy N, Fort J
Service d'Hépato-Gastroentérologie, Centre Hospitalier Général, Le Mans, France.
Gastrointest Endosc. 1997 Jul;46(1):27-32. doi: 10.1016/s0016-5107(97)70205-0.
The aim of this prospective study was to evaluate the interobserver agreement of stigmata of recent hemorrhage of bleeding peptic ulcers.
Sixty-one consecutive adult patients were enrolled in the study and nine (three junior and six senior) endoscopists reviewed standardized video recordings of endoscopic examinations. Interobserver agreement was evaluated using the kappa (kappa) index, intraclass correlation coefficient, and proportion of agreement. Observer bias and poorly trained observers were investigated.
Interobserver agreement was very good for oozing (kappa = 0.68), good for clot (kappa = 0.51), poor for spurting (kappa = 0.29) and visible vessels (kappa = 0.33), and excellent for the absence of stigmata (kappa = 0.82). Observer bias sometimes occurred and the number of poorly trained observers was low. The kappa indexes were significantly better in senior than in junior investigators: 0.48 +/- 0.16 versus 0.37 +/- 0.26, respectively, p < 0.05. The agreement between the in vivo evaluation and video tape recordings (intraobserver agreement) was good (kappa = 0.60 +/- 0.19). There was no training phenomenon between the first and the second half of the patient group.
The endoscopic classification of bleeding ulcers might be simplified by limiting grading to a few classes. Special attention should be paid to the training of endoscopists.
本前瞻性研究的目的是评估消化性溃疡出血近期出血征象的观察者间一致性。
61例成年患者连续纳入本研究,9名(3名初级和6名高级)内镜医师对内镜检查的标准化视频记录进行评估。采用kappa指数、组内相关系数和一致性比例评估观察者间一致性。对观察者偏倚和培训不足的观察者进行调查。
观察者间一致性在渗血方面非常好(kappa = 0.68),血凝块方面良好(kappa = 0.51),喷射性出血方面较差(kappa = 0.29),可见血管方面较差(kappa = 0.33),无出血征象方面极好(kappa = 0.82)。有时会出现观察者偏倚,培训不足的观察者数量较少。高级研究者的kappa指数显著优于初级研究者:分别为0.48±0.16和0.37±0.26,p < 0.05。现场评估与录像之间的一致性(观察者内一致性)良好(kappa = 0.60±0.19)。患者组前半部分和后半部分之间没有训练现象。
通过将分级限制在少数几类,出血性溃疡的内镜分类可能会简化。应特别注意内镜医师的培训。