Takahashi H, Honjo I, Naito Y, Miura M, Tanabe M, Hasebe S, Toda H
Department of Hearing and Speech Science, Kyoto University Graduate School of Medicine, Sakyo-ku, Japan.
Laryngoscope. 1997 Aug;107(8):1117-21. doi: 10.1097/00005537-199708000-00020.
Gas exchange function through the mastoid mucosa was investigated in ears after surgery using nitrous oxide. Increase in the mastoid pressure was assessed by a micropressure sensor placed in the mastoid cavity during the second-stage revision operation performed under general anesthesia using 67% nitrous oxide, 33% oxygen, and sevoflurane on 14 ears with chronic adhesive otitis media or cholesteatoma as well as on seven ears without inflammation as controls. All seven control ears showed pressure increase in the mastoid in various degrees. In the 14 postoperative ears, nine of the 10 ears on which the mastoid mucosa had previously been able to be preserved in various degrees showed pressure increase in the mastoid, but none of the remaining four ears, which had previously had mastoidectomy, showed any pressure increase. The presence or absence of the mastoid pressure increase of those ears was also found to be correlated well with the presence or absence of mastoid aeration on computed tomography examined just before the second-stage operation. These results appear to indicate that, in ears after surgery, recovery of both the gas exchange function and aeration in the mastoid is expected only when the mastoid mucosa can be preserved even partially.
使用氧化亚氮对手术后耳朵通过乳突黏膜的气体交换功能进行了研究。在全身麻醉下对14例慢性粘连性中耳炎或胆脂瘤患者以及7例无炎症的对照患者的耳朵进行二期翻修手术时,通过置于乳突腔内的微压力传感器评估乳突压力的增加情况,手术中使用67%氧化亚氮、33%氧气和七氟醚。所有7例对照耳朵均显示乳突压力有不同程度的增加。在14例术后耳朵中,10例之前乳突黏膜曾不同程度得以保留的耳朵中有9例显示乳突压力增加,但其余4例之前做过乳突切除术的耳朵均未显示任何压力增加。还发现这些耳朵乳突压力增加与否与二期手术前计算机断层扫描显示的乳突气房情况密切相关。这些结果似乎表明,在手术后的耳朵中,只有当乳突黏膜即使部分得以保留时,才有望恢复乳突的气体交换功能和气房形成。