探索蛋白质构象景观：通过氢交换研究部分折叠的蛋白质
Touring the landscapes: partially folded proteins examined by hydrogen exchange.
作者信息
Chamberlain A K, Marqusee S
机构信息
Department of Molecular and Cell Biology, University of California Berkeley 94720, USA.
出版信息
Structure. 1997 Jul 15;5(7):859-63. doi: 10.1016/s0969-2126(97)00240-2.
PMID:9261079
Abstract
Recent studies on Escherichia coli ribonuclease H and several other proteins reveal a specific region in each protein that remains structured in partially folded conformations. These regions play a dominant role in determining the fold and stability of the protein.
摘要
最近对大肠杆菌核糖核酸酶H和其他几种蛋白质的研究揭示了每种蛋白质中的一个特定区域，该区域在部分折叠构象中保持结构。这些区域在决定蛋白质的折叠和稳定性方面起主导作用。
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