Mack M, Acuff T, Yong P, Jett G K, Carter D
Columbia Hospital at Medical City Dallas, TX, USA.
Eur J Cardiothorac Surg. 1997 Jul;12(1):20-4. doi: 10.1016/s1010-7940(97)00141-3.
Minimally invasive techniques have been widely used in other surgical fields including video-assisted thoracic surgery (VATS) in thoracic surgery. These concepts are now being applied to cardiac surgery. The opportunities to make cardiac surgery less invasive include elimination of the median sternotomy incision, elimination of cardiopulmonary bypass and no manipulation of the aorta.
From January 1992 through September 1996, various aspects of minimally invasive cardiac surgery have been examined in the inanimate endoscopic trainer, animal model, human cadaver and in human clinical studies. Techniques of endoscopic sutured anastomosis as well as alternatives to suturing were first perfected in the inanimate trainer. Twenty animals then underwent endoscopic coronary artery bypass using the left internal mammary artery to the left anterior descending with circulatory support from an axial flow pump. Fifty eight minimally invasive coronary artery bypass procedures have been performed in humans using thoracoscopic assistance for internal mammary artery harvest.
One hundred fifty endoscopic coronary anastomoses were performed in the inanimate trainer with the endoscopic suturing technique being the preferred method. Time required to perform an anastomosis decreased from greater than 60 min to a mean of 20 min as technique and instruments were developed. In animals, methods of access as well as enabling surgical instruments to allow crossclamp of the aorta and performance of the anastomosis were developed. Fifty-eight humans underwent coronary artery bypass using the left internal mammary artery placed to the left anterior descending under direct vision through a limited anterior thoracotomy on a beating heart. The procedure was successful in 52 patients with conversions required in six patients. Techniques were developed for immobilization for performance of the anastomosis.
The ability to perform an endoscopic anastomosis still remains the rate limiting step for totally endoscopic coronary artery bypass surgery. The present MIDCAB (minimally invasive direct coronary artery bypass grafting) procedure is a significant advance in cardiac surgery, but still has limitations that make performance of an exact anastomosis still somewhat difficult and applicable only to single-vessel disease. Present efforts are directed toward extending the MIDCAB procedure by various immobilization and circulatory support devices and combining the MIDCAB procedure with catheter techniques for treating more advanced disease.
微创技术已在包括胸外科电视辅助胸腔镜手术(VATS)在内的其他外科领域广泛应用。目前这些理念正被应用于心脏外科手术。使心脏手术创伤更小的机会包括消除正中胸骨切开切口、消除体外循环以及不对主动脉进行操作。
从1992年1月至1996年9月,在无生命的内镜训练器、动物模型、人体尸体以及人体临床研究中对微创心脏手术的各个方面进行了研究。内镜缝合吻合技术以及缝合替代技术首先在无生命的训练器中得以完善。随后20只动物接受了内镜下冠状动脉搭桥术,使用左乳内动脉至左前降支,并由轴流泵提供循环支持。利用胸腔镜辅助获取乳内动脉,已在人体中进行了58例微创冠状动脉搭桥手术。
在无生命的训练器中进行了150例内镜冠状动脉吻合术,内镜缝合技术是首选方法。随着技术和器械的发展,进行一次吻合所需的时间从超过六十分钟降至平均20分钟。在动物实验中,开发了进入途径以及使手术器械能够对主动脉进行交叉钳夹并完成吻合的方法。58例患者通过有限的前外侧开胸在跳动的心脏直视下将左乳内动脉置于左前降支进行冠状动脉搭桥术。52例患者手术成功,6例患者需要中转。开发了用于固定以进行吻合的技术。
进行内镜吻合的能力仍然是完全内镜冠状动脉搭桥手术的限速步骤。目前的微创直接冠状动脉搭桥术(MIDCAB)是心脏外科手术的一项重大进展,但仍存在局限性,使得精确吻合的操作仍有些困难,并且仅适用于单支血管病变。目前的努力方向是通过各种固定和循环支持装置扩展MIDCAB手术,并将MIDCAB手术与导管技术相结合以治疗更晚期的疾病。