Kan A K, Abdalla H I, Oskarsson T
Fertility and Endocrinology Centre, In Vitro Fertilisation Unit, Lister Hospital, London, UK.
Hum Reprod. 1997 Jul;12(7):1434-5. doi: 10.1093/humrep/12.7.1434.
Two successful pregnancies (singleton followed by twins) following ovum donation/in-vitro fertilization in a 46,XY woman have been studied. Although similar cases have previously been presented: in a pure XY patient and in a 45,X/46,XY patient, this case is one in which a subsequent successful pregnancy has resulted. In such patients, the rate of Caesarean section appears to be increased, and we postulate that the hypoplastic nature of the uterus, although able to respond quite well to both exogenous and endogenous hormones to accept and maintain a pregnancy, may lack the capability to respond fully in labour by dilating appropriately.
对一名46,XY女性在接受卵子捐赠/体外受精后成功孕育两胎（一胎单胎，一胎双胞胎）的情况进行了研究。尽管此前已有类似病例报道：一例为单纯XY患者，另一例为45,X/46,XY患者，但该病例成功孕育了后续胎儿。在此类患者中，剖宫产率似乎有所增加，我们推测子宫发育不全，尽管对外源性和内源性激素均能产生良好反应以接受和维持妊娠，但在分娩时可能缺乏充分扩张的能力。
