Department of Obstetrics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Department of Urology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
J Perinat Med. 2021 Mar 17;49(6):725-732. doi: 10.1515/jpm-2020-0562. Print 2021 Jul 27.
For women with Swyer Syndrome, a 46,XY gonadal dysgenesis, full term pregnancies are possible after oocyte donation. According to literature, mode of delivery is almost always by Caesarean section for various reasons. Medical indications are multiple pregnancies and related complications, preeclampsia, an androgynous shaped pelvis and failed induction of labor. Elective Caesarean sections were performed based on maternal request and medical recommendation.
Following careful examination and shared decision making, we planned a spontaneous delivery with a patient with Swyer syndrome and tested the different hypotheses regarding anatomical and functional features according to literature. In addition, deliveries of women with Swyer Syndrome were analyzed in a German multicenter case series.
A total of seven women with Swyer syndrome with a total of 10 pregnancies were identified, who later gave birth to twelve live-born children. Seven out of 10 births were performed by elective and non-elective Caesarean section, three births took place vaginally.
In summary, the risk of Caesarean section delivery has increased, but spontaneous delivery can be attempted in the event of inconspicuous findings.
对于患有 Swyer 综合征（46，XY 性腺发育不全）的女性，通过捐卵可以实现足月妊娠。根据文献，由于各种原因，几乎所有的分娩方式都是剖宫产。医学指征包括多胎妊娠及相关并发症、子痫前期、两性骨盆形态和引产失败。基于产妇的要求和医疗建议，行选择性剖宫产术。
我们对一名患有 Swyer 综合征的患者进行了仔细检查和共同决策，计划进行自然分娩，并根据文献测试了关于解剖和功能特征的不同假设。此外，我们还对德国多中心病例系列中的 Swyer 综合征女性分娩进行了分析。
共确定了 7 名患有 Swyer 综合征的女性，共 10 次妊娠，后来生育了 12 名活产儿。10 次分娩中有 7 次是通过选择性和非选择性剖宫产，3 次是阴道分娩。
总之，剖宫产分娩的风险增加了，但如果没有明显的发现，可以尝试自然分娩。
