Liu S K, Hwu H G, Chen W J
Department of Psychiatry, College of Medicine, National Taiwan University, Taipei.
Schizophr Res. 1997 Jun 20;25(3):211-9. doi: 10.1016/s0920-9964(97)00026-1.
We examined the relationships between symptom dimensions derived from factor analytic studies of schizophrenic symptoms and sustained attention deficits. Four factors, negative, delusion/hallucination, disorganization, and excitement, were yielded from factor analysis on 14 items of the Positive and Negative Syndrome Scale (PANSS) among 60 Chinese inpatients with acute schizophrenia. The negative dimension was associated with lower sensitivity index (d') while the excitement dimension was associated with higher d' on the Continuous Performance Test (CPT) after sex, age and education were adjusted for in multiple linear regressions. The positive dimension affected only response criterion (ln beta) and was not associated with the d' on the CPT. In contrast, the summed scores of PANSS Positive and Negative scales did not have significant correlations with d' on the CPT. Thus, the discriminant validity of these symptom dimensions of schizophrenia is supported by their correlations with CPT performance indices.
我们研究了精神分裂症症状的因素分析研究得出的症状维度与持续性注意力缺陷之间的关系。对60名中国急性精神分裂症住院患者的阳性和阴性症状量表（PANSS）的14个项目进行因素分析，得出了四个因素，即阴性、妄想/幻觉、紊乱和兴奋。在多元线性回归中对性别、年龄和教育程度进行调整后，阴性维度与较低的敏感性指数（d'）相关，而兴奋维度与连续性能测试（CPT）中较高的d'相关。阳性维度仅影响反应标准（ln beta），与CPT上的d'无关。相比之下，PANSS阳性和阴性量表的总分与CPT上的d'没有显著相关性。因此，精神分裂症这些症状维度与CPT表现指标的相关性支持了它们的判别效度。
