Ecker J L, Musci T J
Department of Obstetrics, University of California, San Francisco, USA.
Obstet Gynecol Clin North Am. 1997 Sep;24(3):575-89. doi: 10.1016/s0889-8545(05)70323-5.
With appropriate therapy, complications related to thyroid disease in pregnancy can be minimized. Although the diagnosis of thyroid endocrinopathy may be difficult in pregnancy, few therapies are contra-indicated. Because medications may cross the placenta, however, clinicians need always to be mindful of potential fetal effects and should work to use the minimal dose necessary to achieve maternal euthyroidism. Thyroid function tests, in particular free T4 and TSH, remain good measures of thyroid function and therapy in pregnancy.
通过适当的治疗，与妊娠期间甲状腺疾病相关的并发症可以降至最低。虽然妊娠期间甲状腺内分泌病的诊断可能困难，但几乎没有治疗是禁忌的。然而，由于药物可能会穿过胎盘，临床医生需要始终留意潜在的胎儿影响，并应努力使用实现母体甲状腺功能正常所需的最小剂量。甲状腺功能测试，特别是游离T4和促甲状腺激素，仍然是评估妊娠期间甲状腺功能和治疗效果的良好指标。
