Bosio P, Keenan E, Gleeson R, Dorman A, Clarke T, Darling M, O'Connor J
Rotunda Hospital, Dublin.
Ir Med J. 1997 Jun-Jul;90(4):149-50.
To determine the prevalence of illicit drug abuse and alcohol use in an obstetric population based in an urban maternity hospital.
A collaborative study between the Rotunda Hospital, Dublin and the Irish National Drug Advisory & Treatment Centre.
A prospective study consisting of anonymous, unlinked urine testing of 504 'first visit' antenatal patients and a separate group of 515 patients six weeks after delivery.
METHODS & OUTCOME MEASURES: Toxicological screening using enzyme-linked immunoassay techniques, with all positive samples being reanalysed. Drug histories were taken and samples were tested for alcohol and six of the most commonly abused drugs. The pre- and postnatal prevalence of abuse was matched with demographic data.
The prevalence of chemical substance misuse in the antenatal population was 2.8% and 5.6% in the postnatal population. Substances identified included benzodiazepines, cannabis, amphetamines, opiates and cocaine. Less than 2% of samples tested positive for alcohol. None of the women yielding positive samples had been pre-identified on the basis of history. A significant proportion of the women were in the high risk categories with regard to age and socio-economic status.
The prevalence of drug misuse antenatally was nearly 3% and postnatally almost 6%. Substance abusers in pregnancy are more likely to be single, unemployed, and to have had a previous pregnancy.
确定一家城市妇产医院产科人群中非法药物滥用和酒精使用的流行情况。
都柏林罗通达医院与爱尔兰国家药物咨询与治疗中心之间的一项合作研究。
一项前瞻性研究，包括对504名“首次就诊”的产前患者进行匿名、不关联的尿液检测，以及对另一组515名产后六周的患者进行检测。
采用酶联免疫分析技术进行毒理学筛查，所有阳性样本均重新分析。记录用药史，并对样本进行酒精和六种最常被滥用药物的检测。将产前和产后滥用的流行情况与人口统计学数据进行匹配。
产前人群中化学物质滥用的流行率为2.8%，产后人群中为5.6%。检测出的物质包括苯二氮卓类、大麻、苯丙胺、阿片类药物和可卡因。检测出酒精阳性的样本不到2%。所有呈阳性样本的女性在病史方面之前均未被识别。很大一部分女性在年龄和社会经济地位方面属于高危类别。
产前药物滥用的流行率接近3%，产后接近6%。孕期药物滥用者更可能是单身、失业且有过先前妊娠史。
Zotero 插件