Onishi S, Oda H, Nakaya H, Hatakeyama S, Kumagai K, Choi G H, Kobayashi T, Kamiya K, Miyagishima T, Shinpo K, Ito T
Department of Internal Medicine, Kushiro Rosai Hospital.
Rinsho Ketsueki. 1997 Jul;38(7):582-6.
A 67-year-old man was admitted to with severe nasal congestion. One year previously, he had been suffered from polymyositis (PM) and had been treated with prednisolone. Physical examination and computed tomography revealed a mass in the upper pharynx. Biopsy revealed non-Hodgkin's lymphoma (diffuse medium, B-cell type). Bone marrow aspiration also revealed the infiltration by lymphoma cells. The patient achieved a complete remission after combination chemotherapy (cyclophosphamide, adriamycin, vincristine, prednisolone). However, one month later, he suffered from central nervous system involvement of lymphoma cells, and he died of an aspiration pneumonia. Polymyositis/dermatomyositis associated with non-Hodgkin's lymphoma is extremely rare.
一名67岁男性因严重鼻塞入院。一年前,他患有多发性肌炎(PM),并接受了泼尼松龙治疗。体格检查和计算机断层扫描显示上咽部有一个肿块。活检显示为非霍奇金淋巴瘤(弥漫性中等,B细胞型)。骨髓穿刺也显示有淋巴瘤细胞浸润。患者在联合化疗(环磷酰胺、阿霉素、长春新碱、泼尼松龙)后达到完全缓解。然而,一个月后,他出现淋巴瘤细胞累及中枢神经系统,并死于吸入性肺炎。与非霍奇金淋巴瘤相关的多发性肌炎/皮肌炎极为罕见。