患有人类免疫缺陷病毒相关性痴呆综合征个体的言语信息记忆。美国国立神经疾病与中风研究所艾滋病痴呆症协作研究组。

Memory for verbal information in individuals with HIV-associated dementia complex. HNRC Group.

作者信息

White D A, Taylor M J, Butters N, Mack C, Salmon D P, Peavy G, Ryan L, Heaton R K, Atkinson J H, Chandler J L, Grant I

机构信息

Department of Psychiatry, University of California, San Diego, USA.

出版信息

J Clin Exp Neuropsychol. 1997 Jun;19(3):357-66. doi: 10.1080/01688639708403864.

DOI:10.1080/01688639708403864

PMID:9268810

Abstract

Patterns of memory performance were examined for 9 participants with HIV-associated dementia (HAD), 15 HIV-seropositive participants without dementia, and 15 HIV-seronegative controls. Episodic and semantic memory were assessed using the California Verbal Learning Test, the Boston Naming Test, and Verbal Fluency tests. The HAD group showed deficits in episodic memory, with relative sparing of semantic memory. In addition, results suggest a retrieval deficit in HAD rather than a deficit in retention of information. This pattern is consistent with the presence of a subcortical dementing process and supports findings from previous neuropathological, neuroimaging, and neuropsychological studies suggesting that subcortical brain dysfunction is frequently associated with HIV disease (e.g., Navia, Jordan, & Price, 1986).

摘要

对9名患有人类免疫缺陷病毒相关痴呆症（HAD）的参与者、15名无痴呆症的HIV血清反应阳性参与者和15名HIV血清反应阴性对照者的记忆表现模式进行了研究。使用加利福尼亚言语学习测试、波士顿命名测试和言语流畅性测试对情景记忆和语义记忆进行评估。HAD组在情景记忆方面存在缺陷，语义记忆相对保留。此外，结果表明HAD存在检索缺陷而非信息保留缺陷。这种模式与皮质下痴呆过程的存在相一致，并支持先前神经病理学、神经影像学和神经心理学研究的结果，这些研究表明皮质下脑功能障碍经常与HIV疾病相关（例如，Navia、Jordan和Price，1986年）。