Caffarelli C, Cataldi R, Giordano S, Cavagni G
Department of Pediatrics, University of Parma, Italy.
Allergy Asthma Proc. 1997 Jul-Aug;18(4):245-8. doi: 10.2500/108854197778594007.
In some patients, exercise-induced anaphylactic (EIAn) reactions occur only when a particular food is eaten before exercise. We describe three patients with EIAn induced by different foods. Patients who presented episodes of EIAn performed exercise challenges after fasting and 1 hour after a meal without foods suspected of predisposing the reaction. Subsequently, patients performed exercises after separate intake of each suspected food. Patients underwent skin prick tests (SPT) with food extracts. Serum total and specific IgE antibodies to food were determined. No reactions were provoked by exercise tests without prior intake of suspected foods. Eight of 30 food-exercise combination challenges were positive. In Patient 1, tomato, zucchini, and wheat resulted in adverse reactions: in Patient 2, potato, peanuts, and tomato; in Patient 3, rice and peanuts. SPTs and RASTs to foods predisposing the reaction were positive. Food-exercise combined challenge may be useful in identifying foods that favor EIAn in children with multiple food-dependent EIAn.
在一些患者中，运动诱发的过敏反应（EIAn）仅在运动前食用特定食物时发生。我们描述了三例由不同食物诱发EIAn的患者。出现EIAn发作的患者在禁食后以及进食不含疑似诱发反应食物的餐后1小时进行运动激发试验。随后，患者在分别摄入每种疑似食物后进行运动。患者接受了食物提取物的皮肤点刺试验（SPT）。测定了血清中食物的总IgE和特异性IgE抗体。在未预先摄入疑似食物的情况下，运动试验未引发反应。30次食物 - 运动联合激发试验中有8次呈阳性。在患者1中，番茄、西葫芦和小麦导致不良反应；在患者2中，土豆、花生和番茄；在患者3中，大米和花生。对诱发反应的食物进行的SPT和放射性变应原吸附试验（RAST）呈阳性。食物 - 运动联合激发试验可能有助于识别在患有多种食物依赖型EIAn的儿童中诱发EIAn的食物。
