Localization of the gene encoding a novel isoform of lysyl hydroxylase.

作者信息

Szpirer C, Szpirer J, Rivière M, Vanvooren P, Valtavaara M, Myllylä R

机构信息

Département de Biologie Moléculaire, Université Libre de Bruxelles, Rue des Chevaux, 67, B-1640 Rhode-St-Genèse, Belgium.

出版信息

Mamm Genome. 1997 Sep;8(9):707-8. doi: 10.1007/s003359900549.

DOI:10.1007/s003359900549

PMID:9271685

Abstract

摘要

相似文献

Localization of the gene encoding a novel isoform of lysyl hydroxylase.

Mamm Genome. 1997 Sep;8(9):707-8. doi: 10.1007/s003359900549.

The genes encoding mouse lysyl hydroxylase isoforms map to chromosomes 4,5, and 9.编码小鼠赖氨酰羟化酶同工型的基因定位于4号、5号和9号染色体。

Mamm Genome. 2000 Dec;11(12):1132-4. doi: 10.1007/s003350010214.

Cloning of human lysyl hydroxylase: complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3----p36.2.人赖氨酰羟化酶的克隆：完整的cDNA推导的氨基酸序列及该基因（PLOD）定位于染色体1p36.3----p36.2。

Genomics. 1992 May;13(1):62-9. doi: 10.1016/0888-7543(92)90202-4.

Cloning and characterization of a novel human lysyl hydroxylase isoform highly expressed in pancreas and muscle.一种在胰腺和肌肉中高表达的新型人类赖氨酰羟化酶亚型的克隆与特性分析。

J Biol Chem. 1997 Mar 14;272(11):6831-4. doi: 10.1074/jbc.272.11.6831.

Cloning and characterization of a third human lysyl hydroxylase isoform.第三种人赖氨酰羟化酶同工型的克隆与特性分析

Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10482-6. doi: 10.1073/pnas.95.18.10482.

Molecular cloning of chick lysyl hydroxylase. Little homology in primary structure to the two types of subunit of prolyl 4-hydroxylase.

J Biol Chem. 1991 Feb 15;266(5):2805-10.

The let-268 locus of Caenorhabditis elegans encodes a procollagen lysyl hydroxylase that is essential for type IV collagen secretion.秀丽隐杆线虫的let-268基因座编码一种原胶原赖氨酸羟化酶，该酶对于IV型胶原的分泌至关重要。

Dev Biol. 2000 Nov 15;227(2):690-705. doi: 10.1006/dbio.2000.9897.

A large duplication in the gene for lysyl hydroxylase accounts for the type VI variant of Ehlers-Danlos syndrome in two siblings.赖氨酸羟化酶基因的大片段重复导致了两名同胞患埃勒斯-当洛综合征VI型变异。

Genomics. 1993 Feb;15(2):399-404. doi: 10.1006/geno.1993.1074.

Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse.小鼠赖氨酰羟化酶1、2和3的cDNA特性、系统发育分析及其在小鼠中的组织特异性表达

Matrix Biol. 1999 Jun;18(3):325-9. doi: 10.1016/s0945-053x(99)00016-5.

Structure and expression of the human lysyl hydroxylase gene (PLOD): introns 9 and 16 contain Alu sequences at the sites of recombination in Ehlers-Danlos syndrome type VI patients.人赖氨酰羟化酶基因（PLOD）的结构与表达：在Ⅵ型埃勒斯-当洛综合征患者的重组位点，第9和16内含子含有Alu序列。

Genomics. 1994 Dec;24(3):464-71. doi: 10.1006/geno.1994.1654.

引用本文的文献

Bioinformatic analysis of PLOD family member expression and prognostic value in non-small cell lung cancer.PLOD家族成员在非小细胞肺癌中的表达及预后价值的生物信息学分析

Transl Cancer Res. 2021 Jun;10(6):2707-2724. doi: 10.21037/tcr-21-73.

A Novel Six-Gene-Based Prognostic Model Predicts Survival and Clinical Risk Score for Gastric Cancer.一种基于六个基因的新型预后模型预测胃癌的生存率和临床风险评分。

Front Genet. 2021 Feb 22;12:615834. doi: 10.3389/fgene.2021.615834. eCollection 2021.

Roles of PLODs in Collagen Synthesis and Cancer Progression.赖氨酰氧化酶家族蛋白在胶原蛋白合成及癌症进展中的作用

Front Cell Dev Biol. 2018 Jun 28;6:66. doi: 10.3389/fcell.2018.00066. eCollection 2018.

New perspectives on osteogenesis imperfecta.成骨不全症的新视角。

Nat Rev Endocrinol. 2011 Jun 14;7(9):540-57. doi: 10.1038/nrendo.2011.81.

Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17.布鲁克综合征中骨组织而非韧带或软骨中的胶原蛋白交联缺陷：17号染色体上骨特异性端肽赖氨酰羟化酶的指征

Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1054-8. doi: 10.1073/pnas.96.3.1054.

本文引用的文献

J Biol Chem. 1997 Mar 14;272(11):6831-4. doi: 10.1074/jbc.272.11.6831.

The rat: an experimental animal in search of a genetic map.

Folia Biol (Praha). 1996;42(4):175-226.

Chromosomal assignment of three rat and human H-rev genes, putative tumor suppressors, down-regulated in malignantly HRAS-transformed cells.在恶性HRAS转化细胞中表达下调的三个大鼠和人类H-rev基因（假定的肿瘤抑制基因）的染色体定位。

Mamm Genome. 1996 Sep;7(9):701-3. doi: 10.1007/s003359900211.

The rat genes encoding the pancreatitis-associated proteins I, II and III (Pap1, Pap2, Pap3), and the lithostathin/pancreatic stone protein/regeneration protein (Reg) colocalize at 4q33-->q34.编码胰腺炎相关蛋白I、II和III（Pap1、Pap2、Pap3）以及抑石素/胰腺结石蛋白/再生蛋白（Reg）的大鼠基因共定位于4q33→q34。

Cytogenet Cell Genet. 1996;72(1):83-5. doi: 10.1159/000134168.

High-resolution fluorescence mapping of 46 DNA markers to the short arm of human chromosome 1.

Genomics. 1993 Oct;18(1):71-8. doi: 10.1006/geno.1993.1427.

A rat genetic linkage map and comparative maps for mouse or human homologous rat genes.一张大鼠遗传连锁图谱以及小鼠或人类同源大鼠基因的比较图谱。

Mamm Genome. 1994 Feb;5(2):63-83. doi: 10.1007/BF00292332.

A patient with Ehlers-Danlos syndrome type VI is a compound heterozygote for mutations in the lysyl hydroxylase gene.患有Ⅵ型埃勒斯-当洛综合征的患者是赖氨酸羟化酶基因突变的复合杂合子。

J Clin Invest. 1994 Apr;93(4):1716-21. doi: 10.1172/JCI117155.

Alu-Alu recombination results in a duplication of seven exons in the lysyl hydroxylase gene in a patient with the type VI variant of Ehlers-Danlos syndrome.在一名患有埃勒斯-当洛综合征VI型变体的患者中，Alu-Alu重组导致赖氨酸羟化酶基因中的七个外显子发生重复。

Am J Hum Genet. 1994 Nov;55(5):899-906.

Collagens: molecular biology, diseases, and potentials for therapy.胶原蛋白：分子生物学、疾病及治疗潜力

Annu Rev Biochem. 1995;64:403-34. doi: 10.1146/annurev.bi.64.070195.002155.

A heritable disorder of connective tissue. Hydroxylysine-deficient collagen disease.一种遗传性结缔组织疾病。羟赖氨酸缺乏性胶原病。

N Engl J Med. 1972 May 11;286(19):1013-20. doi: 10.1056/NEJM197205112861901.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验