Hossain A M, Bhaumik D, Selukar R, Huff C, Rizk B, Thorneycroft I H
Department of Obstetrics and Gynecology, University of South Alabama, Mobile 36688, USA.
Arch Androl. 1997 Sep-Oct;39(2):111-7. doi: 10.3109/01485019708987909.
The occurrence of abnormal forms of spermatozoa in human semen is quite common. According to WHO, semen is considered normal even if it contains 50% morphologically abnormal spermatozoa. This study assessed whether the sperm morphology maintains any relation with the relevant clinical conditions of the semen donor. One hundred samples representing normal and different types of male factor etiologies underwent semen and morphological analysis. Clinical information such as race, age, weight, profession, medication, medical history, and smoking habit of the semen contributors were recorded. The influence of seminal and clinical features on sperm morphology was evaluated with multiple regression analysis. Head abnormalities were more common than tail abnormalities. Acrosomal defects and coiled tails were the most prevalent head and tail abnormalities, respectively. Regression analysis failed to confirm any strong association between sperm morphology and other seminal parameters. Accessory gland-related seminal parameters such as viscosity, volume, pH, and liquefaction showed the least association with the morphological variability. Sperm morphology also showed poor correlation with race, age, weight, smoking habit, and work environment.
人类精液中出现异常形态的精子相当常见。根据世界卫生组织的标准，即使精液中含有50%形态异常的精子，也被认为是正常的。本研究评估了精子形态与精液捐献者的相关临床状况是否存在任何关联。对代表正常及不同类型男性因素病因的100份样本进行了精液和形态学分析。记录了精液捐献者的种族、年龄、体重、职业、用药情况、病史和吸烟习惯等临床信息。采用多元回归分析评估精液和临床特征对精子形态的影响。头部异常比尾部异常更常见。顶体缺陷和卷曲尾部分别是最常见的头部和尾部异常。回归分析未能证实精子形态与其他精液参数之间存在任何强关联。与附属腺相关的精液参数，如粘度、体积、pH值和液化，与形态变异性的关联最小。精子形态与种族、年龄、体重、吸烟习惯和工作环境的相关性也很差。
