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[儿童弓蛔虫病的临床病程及治疗]

[Clinical course and treatment of toxocariasis in children].

作者信息

Marczyńska M

机构信息

Kliniki Chorób Zakaźnych Wieku Dzieclecego A.M. w Warszawie.

出版信息

Pol Merkur Lekarski. 1996 Dec;1(6):377-8.

PMID:9273224
Abstract

Toxocariasis is a parasitic disease. Larvae of Toxocara canis, as intra-tissular parasites, can survive in human organism for 10 years. Clinical symptoms depend on massiveness of infection, organ localisation and defensive reactions of patients. 74 children were observed (in age from 1 year 8 months to 15 years). 70% of them had intraocular lesions which is the most serious complication of toxocariasis. Larva of T. canis is neurotropic. EEG revealed abnormalities in 73% of patients. The diagnosis of toxocariasis was confirmed by immunoenzymatic reaction ELISA with T. canis antigen. The patients were treated with hetrazan, if intraocular lesions were present prednisone was added. Improvement was achieved in 78% of children with intraocular lesions, in the rest effectiveness of the treatment is questionable.

摘要

弓蛔虫病是一种寄生虫病。犬弓蛔虫的幼虫作为组织内寄生虫,可在人体内存活10年。临床症状取决于感染的严重程度、器官定位以及患者的防御反应。观察了74名儿童(年龄从1岁8个月至15岁)。其中70%有眼部病变,这是弓蛔虫病最严重的并发症。犬弓蛔虫幼虫具有嗜神经性。脑电图显示73%的患者有异常。通过用犬弓蛔虫抗原进行免疫酶反应ELISA确诊为弓蛔虫病。如果有眼部病变,患者用海群生治疗,并加用泼尼松。78%有眼部病变的儿童病情有所改善,其余患者治疗效果存疑。

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