Jobba G, Bajnóczky I, Földes V, Kósa F, Szilvásy L, Leinzinger L, Unger L, Vörös M
Morphol Igazsagugyi Orv Sz. 1977 Jul;17(3):211-6.
Five cases of amnion fluid embolism are reported. In the first case the cause of the death was the obstruction of the lung-vessels. In the lung tissue calcium embolia could also been detected. In the second case embolization started--at unruptured amnionsac--with ecclampsia-like convulsions, later it was followed by coagulopathia. In the third case amnion fluid embolism was complicated by coagulopathia. In the fourth case in addition to amnion fluid embolism endometritis purulenta complicated by endotoxinaemia and coagulopathia were also present. In all four cases rupture of the uterus was revealed. In the fifth case amnion fluid embolism developed without the rupture of the uterus. At the autopsy of cases of maternal death the possibility of amnion fluid embolism should always be considered. Although macroscopic changes seen at amnion fluid embolism are not pathognomic, when clinical and pathological symptoms of haemorrhagic diathesis are present, there always arises the suspicion of amnion fluid embolism. Since lungs are relatively resistant to putrefaction amnion fluid embolism in optimal cases can be diagnosed histologically even in exhumated lung specimen. Reliable diagnosis of amnion fluid embolism in cases of sudden maternal death gives possibility to exclude medical negligence.
报告了5例羊水栓塞病例。第一例死亡原因是肺血管阻塞。在肺组织中也检测到了钙栓子。第二例栓塞始于未破裂的羊膜囊,伴有子痫样惊厥,随后出现凝血障碍。第三例羊水栓塞并发凝血障碍。第四例除羊水栓塞外,还存在脓性子宫内膜炎并发内毒素血症和凝血障碍。在所有4例中均发现子宫破裂。第五例羊水栓塞发生时子宫未破裂。在产妇死亡病例的尸检中,应始终考虑羊水栓塞的可能性。虽然羊水栓塞时所见的宏观变化并非特异性,但当出现出血素质的临床和病理症状时,总是会怀疑羊水栓塞。由于肺对腐败相对有抵抗力,即使在挖掘出的肺标本中,在最佳情况下也可通过组织学诊断羊水栓塞。在产妇突然死亡的病例中,对羊水栓塞进行可靠诊断有可能排除医疗过失。