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紫外线A光疗治疗日光性荨麻疹后的长期获益

Prolonged benefit following ultraviolet A phototherapy for solar urticaria.

作者信息

Dawe R S, Ferguson J

机构信息

Department of Dermatology, Ninewells Hospital and Medical School, Dundee, Scotland, U.K.

出版信息

Br J Dermatol. 1997 Jul;137(1):144-8.

PMID:9274644
Abstract

Two patients with severe idiopathic solar urticaria, previously resistant to a variety of therapies including plasma exchange, benefited from springtime courses of ultraviolet A (UVA) monotherapy. Sites which are normally exposed to sunlight were treated, in a cabinet fitted with Philips R-UVA lamps (emitting UVA and visible wavelengths, with peak at 350 nm), twice daily for 2-3 weeks. One patient has been treated in this way for 3, and the other for 2, consecutive years. Repeat monochromator phototesting 3 months after their latest courses of UVA showed a persistent reduction in severity of abnormal photosensitivity. Both patients describe a sustained improvement in their condition lasting over 6 months after treatment.

摘要

两名患有严重特发性日光性荨麻疹的患者,此前对包括血浆置换在内的多种治疗均无反应,却从春季的紫外线A(UVA)单一疗法疗程中获益。在一个装有飞利浦R-UVA灯(发射UVA和可见光波长,峰值在350纳米)的治疗舱中,对通常暴露于阳光下的部位进行治疗,每天两次,持续2至3周。一名患者已连续3年接受这种治疗,另一名患者连续2年接受治疗。在他们最近一次UVA疗程结束3个月后进行的重复单色仪光测试显示,异常光敏反应的严重程度持续降低。两名患者均表示治疗后病情持续改善超过6个月。

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