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[关于2-(2'-羟基-3'-叔丁基-5'-甲基苯基)-5-氯苯并三唑的迁移与毒理学的研究贡献]

[Contribution to the migration and toxicology of 2-(2'-hydroxy-3'-tert-butyl-5'-methylpheny)-5-chlorobenzotriazole].

作者信息

Uhde W J, Horácek J

出版信息

Nahrung. 1977;21(8):705-10.

PMID:927485
Abstract

Studies on the use of an ultraviolet-absorbing agent based on hydroxybenzotriazole for commodities of low-pressure and high-pressure polyethylene and polypropylene show that the migration is only slight in aqueous and acidic foods and in foodstuffs with low alcohol content. Sunflower oil, n-heptane (as a fat-stimulating test solution) and 50% ethanol as test solutions yielded higher migration values. Gas chromatographic, polarographic and thin-layer chromatographic methods were used to determine the ultraviolet-absorbing agent. Concerns about a possible photosensitizing effect of 2-(2'-hydroxy-3'-tert-butyl-5'-methylphenyl)-5-chlorobenzotriazole were experimentally tested and turned out to be unfounded. From the viewpoint of safety, there are no contraindications to the use of polyolefines in packing materials for most foods. As to fat-containing and strongly alcoholic foodstuffs, the authorization should be conditioned on the circumstances of use.

摘要

对基于羟基苯并三唑的紫外线吸收剂在低压和高压聚乙烯及聚丙烯商品中的应用研究表明,在水性和酸性食品以及低酒精含量的食品中,迁移量仅为轻微。葵花籽油、正庚烷(作为脂肪刺激测试溶液)和50%乙醇作为测试溶液时,迁移值较高。采用气相色谱法、极谱法和薄层色谱法测定紫外线吸收剂。对2-(2'-羟基-3'-叔丁基-5'-甲基苯基)-5-氯苯并三唑可能的光敏作用的担忧经过实验测试,结果表明是没有根据的。从安全角度来看,在大多数食品的包装材料中使用聚烯烃没有禁忌。对于含脂肪和高酒精含量的食品,应根据使用情况进行授权。

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