Shi Z, Shen P, Shen G
Department of Cardiology, Rui Jin Hospital, Shanghai Second Medical University.
Zhonghua Nei Ke Za Zhi. 1996 Jan;35(1):25-7.
To assess the prevalence of extracranial carotid artery atherosclerosis and its relation to principal cardiovascular risk factors in Chinese elderly patients, 100 cases aged from 54 to 94 were investigated with B-mode ultrasonography. Arterial intima-media thickening, plaque, mild stenosis (defined as a plaque that obstructed > 20% of the lumen diameter), and clinically significant stenosis (> 50% in cross-sectional area) were found in 79, 49, 40 and 3 patients, respectively. There was no significant correlation between carotid atherosclerosis and coronary heart disease, cerebral infarction, hypertension, hyperlipidemia or diabetes. In contrast, the prevalence of carotid atherosclerosis was increased with age (P < 0.05), so did the severity. Thus, age is a major risk factor for carotid atherosclerosis in the elderly.
为评估中国老年患者颅外颈动脉粥样硬化的患病率及其与主要心血管危险因素的关系，对100例年龄在54至94岁之间的患者进行了B型超声检查。分别在79例、49例、40例和3例患者中发现动脉内膜中层增厚、斑块、轻度狭窄（定义为阻塞管腔直径>20%的斑块）和具有临床意义的狭窄（横截面积>50%）。颈动脉粥样硬化与冠心病、脑梗死、高血压、高脂血症或糖尿病之间无显著相关性。相反，颈动脉粥样硬化的患病率随年龄增加而升高（P<0.05），严重程度也是如此。因此，年龄是老年患者颈动脉粥样硬化的主要危险因素。
