Cai Y, Dong H, Weng M
Zhongshan Hospital, Shanghai Medical University.
Zhonghua Nei Ke Za Zhi. 1996 Jan;35(1):41-4.
5 cases with obesity-hypoventilaion syndrome were reported. The clinical manifestations were obesity, palpitation, dyspnea, lethargy, cyanosis, distention of cervical vein, edema, enlargement of liver and hypertension. All of them were initially diagnosed as chronic bronchitis or heart diseases. Pulmonary function test showed restrictive ventilative defect and hypercapnia with hypoxemia. Mouth oclusion pressure at 0.1 second was higher than the normal value. The response to CO2 was decreased. Hypertrophy of right heart was shown in ECG and X-ray film improvement in symptoms and blood gases analyses were found to be associated with body weight decrease in a follow up period of one year.
报告了5例肥胖低通气综合征患者。临床表现为肥胖、心悸、呼吸困难、嗜睡、发绀、颈静脉怒张、水肿、肝脏肿大和高血压。他们最初均被诊断为慢性支气管炎或心脏病。肺功能测试显示限制性通气功能障碍、高碳酸血症伴低氧血症。0.1秒时的口腔闭合压高于正常值。对二氧化碳的反应降低。心电图显示右心室肥厚，X线片显示在一年的随访期内症状改善和血气分析与体重减轻有关。
