Zeng H, Yu S, Gu H, Wang D, Zhao G, Hu F, Hu X, Zhao Z
Department of Internal Medicine, Tongji Hospital, Tongji Medical University, Wuhan.
J Tongji Med Univ. 1996;16(2):87-90. doi: 10.1007/BF02887964.
The effect of domestically-manufactured excimer laser with adjunctive balloon angioplasty in achieving revascularization and reduction of residual stenosis was assessed. 20 femoral arteries with thrombosis and occlusion from 12 dogs were subject to angiography. At first excimer laser angioplasty was done followed by balloon angioplasty. The diameter and residual stenosis of revascularized vessel were measured. The result showed that 17 out of 20 vessels (85%) were revascularized. The diameter of revascularized vessel by excimer laser were 1.22 +/- 0.14 mm, while residual stenoses were 54% +/- 5%. After adjunctive balloon angioplasty the diameter and residual stenoses were 2.04 +/- 0.16 mm and 20% +/- 7% respectively (P < 0.05 and P < 0.01). Complication in form of vasoperforation occurred in 3/20 vessels (15%). It is concluded that China- manufactured excimer laser angioplasty is effective when used for revascularization. While the reduction of narrowing and residual stenoses was enhanced after adjunction of balloon angioplasty. This method can be employed in treating peripheral occlusive disease effectively and safely.
评估国产准分子激光联合球囊血管成形术在实现血管再通和减少残余狭窄方面的效果。对12只犬的20条发生血栓形成和闭塞的股动脉进行血管造影。首先进行准分子激光血管成形术，然后进行球囊血管成形术。测量血管再通后的直径和残余狭窄情况。结果显示，20条血管中有17条（85%）实现了血管再通。准分子激光血管再通后的血管直径为1.22±0.14毫米，而残余狭窄为54%±5%。联合球囊血管成形术后，直径和残余狭窄分别为2.04±0.16毫米和20%±7%（P<0.05和P<0.01）。20条血管中有3条（15%）发生了血管穿孔形式的并发症。结论是，国产准分子激光血管成形术用于血管再通是有效的。球囊血管成形术联合应用后，狭窄和残余狭窄的减少得到增强。该方法可有效、安全地用于治疗周围闭塞性疾病。
