Yu S, Wang D W, Hu X J, Zhao Z S, Wang P L, Liu P T, Cui Y B
J Tongji Med Univ. 1989;9(3):181-6. doi: 10.1007/BF02908972.
Thrombi in test-tube, intraarterial thrombi and pig aorta wall were in vitro irradiated with continuous CO2 laser, short pulsal and ultrashort pulsal YAG laser (with pulse-width of 10 ns and 40 ps, respectively) and their double frequency laser and excimer laser with a wave-length of 308 nm and pulse-width of 20 ns. Their effect of vaporizing and ablating (photodecomposing) thrombi and their thermal injuring effect on adjacent tissues were compared and assessed in order to select optimal laser with little thermal injuring and more rapid vaporizing or ablating thrombi effect for laser angioplasty. The experimental results showed that excimer laser, ultrashort pulsal YAG laser and its double frequency laser, and double frequency laser of short pulsal YAG laser, with laser beam and blood vessel kept in a coaxial position, can effectively vaporize or ablate thrombi without thermal injury to vessel wall. So they may be used for laser angioplasty. Of them, especially, excimer laser and double frequency laser of ultrashort pulsal YAG laser have short wave-length and high peak power, and more effectively ablate thrombi than others, so they proved to be optimal lasers for laser angioplasty.
对试管内血栓、动脉内血栓和猪主动脉壁血栓进行体外照射，照射激光包括连续CO2激光、短脉冲和超短脉冲YAG激光（脉冲宽度分别为10纳秒和40皮秒）及其倍频激光，以及波长为308纳米、脉冲宽度为20纳秒的准分子激光。比较和评估它们对血栓的汽化和消融（光分解）作用及其对相邻组织的热损伤作用，以便为激光血管成形术选择热损伤小、血栓汽化或消融作用更快的最佳激光。实验结果表明，在激光束与血管保持同轴的情况下，准分子激光、超短脉冲YAG激光及其倍频激光、短脉冲YAG激光的倍频激光能有效汽化或消融血栓，而不会对血管壁造成热损伤。因此，它们可用于激光血管成形术。其中，特别是准分子激光和超短脉冲YAG激光的倍频激光，波长较短，峰值功率较高，消融血栓的效果比其他激光更有效，因此被证明是激光血管成形术的最佳激光。
