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A pseudo-outbreak of purified protein derivative skin-test conversions caused by inappropriate testing materials.

作者信息

Grabau J C, Burrows D J, Kern M L

机构信息

Bureau of Tuberculosis Control, New York State Department of Health, Albany 12237-0669, USA.

出版信息

Infect Control Hosp Epidemiol. 1997 Aug;18(8):571-4. doi: 10.1086/647674.

DOI:10.1086/647674
PMID:9276239
Abstract

OBJECTIVE

To investigate a cluster of newly identified tuberculosis infections.

DESIGN

A field study was conducted including interviews; medical record reviews; checking of bills and invoices, pharmacy records, and drug manufacturer information; and clinical retesting.

SETTING

Community residential facilities providing comprehensive services to retarded adults.

PARTICIPANTS

Twenty residential facility staff (not previously known to be purified protein derivative [PPD] positive).

RESULTS

Staff had been tested with 250 TU of PPD, and 9 of 20 were tuberculin positive. Retesting with 5 TU yielded no reaction.

CONCLUSIONS

Reactions were attributable to testing with a product not recommended for routine PPD screening. Healthcare workers planting PPD Mantoux tests always should check the vials to ensure that the appropriate strength solution is being used.

摘要

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Indian J Pediatr. 2017 Sep;84(9):657-659. doi: 10.1007/s12098-017-2451-9. Epub 2017 Aug 11.