Perkins N A, Westfall T C
Neurosci Lett. 1979 Mar;11(3):283-7. doi: 10.1016/0304-3940(79)90009-0.
The ability of acetylcholine to influence the stimulation-induced release of [3H]dopamine in medial basal hypothalamus was evaluated. A muscarinic facilitation of electrical field-stimulated but not potassium-stimulated release was observed. These data suggest a muscarinic enhancement of dopamine release perhaps via an action at the level of the cell body. These data suggest that observed effects of cholinergic agents on prolactin release may be mediated in part through such a cholinergic-dopaminergic interaction.
评估了乙酰胆碱影响内侧基底下丘脑刺激诱导的[3H]多巴胺释放的能力。观察到毒蕈碱对电场刺激而非钾刺激的释放有促进作用。这些数据表明，毒蕈碱可能通过作用于细胞体水平增强多巴胺释放。这些数据表明，胆碱能药物对催乳素释放的观察到的影响可能部分通过这种胆碱能-多巴胺能相互作用介导。
