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多相性过敏反应:1例病例报告及院前和急诊科相关考量

Multiphasic anaphylaxis: report of a case with prehospital and emergency department considerations.

作者信息

Brady W J, Luber S, Joyce T P

机构信息

Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, USA.

出版信息

J Emerg Med. 1997 Jul-Aug;15(4):477-81. doi: 10.1016/s0736-4679(97)00076-0.

DOI:10.1016/s0736-4679(97)00076-0
PMID:9279699
Abstract

Anaphylaxis, a multisystem allergic reaction, represents a true medical emergency. Anaphylaxis is characterized by a combination of the following symptoms: urticaria, angioedema, distributive shock, and respiratory failure. Most often, the patient is rapidly treated with prompt resolution of the anaphylaxis in either the out-of-hospital or emergency department (ED) setting. Infrequently, recurrent or multiphasic anaphylaxis is encountered, involving a reappearance of allergic phenomena after complete resolution of the original reaction. Recurrence may involve nuisance-level issues such as urticaria; alternatively, multiphasic reactions may be characterized by cardiovascular collapse or respiratory compromise. Initially aggressive pharmacological therapy followed by prolonged observation in either the ED or the in-hospital setting is strongly recommended to monitor for potential recurrence.

摘要

过敏反应是一种多系统过敏反应,是真正的医疗急症。过敏反应的特征是以下症状的组合:荨麻疹、血管性水肿、分布性休克和呼吸衰竭。大多数情况下,患者在院外或急诊科能迅速得到治疗,过敏反应也能迅速缓解。但偶尔会遇到复发性或多相性过敏反应,即在最初反应完全缓解后过敏现象再次出现。复发可能涉及如荨麻疹等轻微问题;或者,多相反应可能以心血管衰竭或呼吸功能不全为特征。强烈建议最初进行积极的药物治疗,然后在急诊科或住院环境中进行长时间观察,以监测潜在的复发情况。

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