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Radiation therapy in the management of patients with unresectable stage IIIA and IIIB non-small cell lung cancer.

作者信息

Wagner H

机构信息

H. Lee Moffitt Cancer Center and Research Institute, and the Department of Radiology, University of South Florida, Tampa 33612, USA.

出版信息

Semin Oncol. 1997 Aug;24(4):423-8.

PMID:9280222
Abstract

Treatment of patients with unresectable stage IIIA and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10%. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2-year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.

摘要

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