Sugaya Y, Ochi M, Hashimoto S, Muraki J, Morita T, Kobayashi Y, Nakamura S, Tokue A
Department of Urology, Jichi Medical School.
Hinyokika Kiyo. 1997 Jul;43(7):495-9.
We report a case of transitional cell carcinoma of the renal pelvis with extremely high serum levels of carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA). A 69-year-old woman was admitted with gross hematuria. Imaging diagnosis revealed a tumor in the left renal pelvis and multiple liver and bone metastases. Serum levels of CA19-9 and CEA were 2,557 U/ml (normal < 36) and 523 ng/ml (normal < 3.8), respectively. She died of cancer progression 3 weeks after admission. An autopsy diagnosis was transitional cell carcinoma of the left renal pelvis. No abnormal findings were recognized in the gastrointestinal organs. Cancer cells showed a positive immunohistochemical staining for both CA19-9 and CEA.
我们报告一例肾盂移行细胞癌患者,其血清中糖类抗原19-9(CA19-9)和癌胚抗原(CEA)水平极高。一名69岁女性因肉眼血尿入院。影像学诊断显示左肾盂有肿瘤,并有多处肝转移和骨转移。血清CA19-9和CEA水平分别为2557 U/ml(正常<36)和523 ng/ml(正常<3.8)。入院3周后,她死于癌症进展。尸检诊断为左肾盂移行细胞癌。在胃肠道器官中未发现异常。癌细胞对CA19-9和CEA的免疫组化染色均呈阳性。