Tanaka K, Chokyu H, Sugita Y, Yoshimura K, Umezu K
Department of Urology, Kobe National Hospital.
Hinyokika Kiyo. 1996 May;42(5):365-7.
A case of renal cell carcinoma with extremely high serum carcinoembryonic antigen (CEA) levels is presented. A 57-year-old female complained of left flank pain. Computerized tomographic (CT) scan revealed left renal tumor and laboratory examination revealed an extremely high serum level of CEA (815 ng/ml). No abnormal findings were recognized in gastrointestinal or genital systems. Radical nephrectomy was done. The histology was renal cell carcinoma (RCC, intermediate type, mixed type, pleomorphic cell type, G3 > G2, INF gamma, pT2, pV0). Tumor cells were positive for CEA by ABC-peroxidase staining. Levels of tumor markers decreased after operation. However, CEA levels rose again and lymph node metastases appeared. She died 6 months after operation.
本文报告一例血清癌胚抗原(CEA)水平极高的肾细胞癌病例。一名57岁女性因左侧腰痛就诊。计算机断层扫描(CT)显示左肾肿瘤,实验室检查发现血清CEA水平极高(815 ng/ml)。胃肠道和生殖系统未发现异常。行根治性肾切除术。组织学检查为肾细胞癌(RCC,中间型、混合型、多形细胞型,G3>G2,INFγ,pT2,pV0)。肿瘤细胞经ABC-过氧化物酶染色CEA呈阳性。术后肿瘤标志物水平下降。然而,CEA水平再次升高并出现淋巴结转移。患者术后6个月死亡。