Nozawa M, Seguchi T, Nonomura N, Kokado Y, Miki T, Okuyama A
Department of Urology, Osaka University Medical School.
Hinyokika Kiyo. 1997 Jul;43(7):521-4.
A 26-year-old man presented with a painless mass in the right scrotum. Physical examination revealed another smaller mass in the left testis. The patient underwent right radical orchiectomy and enucleation of the tumor in the left testis, followed by radiotherapy for right iliac and para-aortic lymph nodes up to a total dose of 30 Gy. Histology proved typical seminoma of the right testis and mature teratoma in the left testis. Imaging study including abdominal CT and chest X-ray and prompt lowering of beta-HCG level within the normal limit after surgery confirmed the diagnosis of stage I disease. Human leukocyte antigen (HLA)-A24 was identified in this case, suggesting its potential association with bilateral testicular tumor. He is now leading an uneventful life without recurrence of the disease at 30 months after surgery.
一名26岁男性因右侧阴囊无痛性肿块就诊。体格检查发现左侧睾丸还有一个较小的肿块。患者接受了右侧根治性睾丸切除术及左侧睾丸肿瘤剜除术，随后对右侧髂部和腹主动脉旁淋巴结进行放射治疗，总剂量达30 Gy。组织学检查证实右侧睾丸为典型精原细胞瘤，左侧睾丸为成熟畸胎瘤。包括腹部CT和胸部X线在内的影像学检查以及术后β-HCG水平迅速降至正常范围证实为Ⅰ期疾病。该病例检测出人类白细胞抗原（HLA）-A24，提示其可能与双侧睾丸肿瘤有关。术后30个月，他目前生活平稳，疾病未复发。
