Bunning V K, Lindsay J A, Archer D L
Division of Virulence Assessment, Food and Drug Administration, Laurel, MD, USA.
World Health Stat Q. 1997;50(1-2):51-6.
The acute effects of foodborne disease are sometimes not the end of the illness. Several significant foodborne pathogens are capable of triggering chronic disease, and even permanent tissue or organ destruction, probably via immune mechanisms. Arthritis, septic and reactive, inflammatory bowel disease, haemolytic uraemic syndrome, Guillain-Barré syndrome, and possible several autoimmune disorders can be triggered by foodborne pathogens or their toxins. Research is needed to more fully understand the mechanisms by which the immune system is inappropriately activated by these common foodborne disease-causing agents.
食源性疾病的急性影响有时并非疾病的终结。几种重要的食源性病原体能够引发慢性疾病,甚至导致永久性组织或器官损伤,这可能是通过免疫机制实现的。食源性病原体或其毒素可引发关节炎(感染性和反应性)、炎症性肠病、溶血尿毒综合征、吉兰 - 巴雷综合征,以及可能的几种自身免疫性疾病。需要开展研究以更全面地了解这些常见食源性病原体如何不适当地激活免疫系统的机制。