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[三维正电子发射断层成像系统及其医学应用]

[Three-dimensional positron emission tomography imaging system and its application for medical use].

作者信息

Orihara H, Ishii K, Iwata R, Fujiwara T, Itoh M

机构信息

Cyclotron and Radioisotope Center, Tohoku University.

出版信息

Nihon Rinsho. 1997 Aug;55(8):2148-55.

PMID:9284437
Abstract

Current positron emission tomography is capable for three dimensional data acquisition and reconstruction (3D PET). The main advantage of 3D PET is its detectability for lower tracer concentrations. The images by a 3D PET have better signal to noise ratios compared to those by conventional 2D PET. This point is especially important for the studies of distributions of ligands for neuroreceptors such as F-18 FDOPA and C-11 YM-01951, since these ligands show low accumulation in brain. Reduction of scanning time is useful as well for patients are permitting extended scanning periods

摘要

当前的正电子发射断层扫描能够进行三维数据采集和重建(3D PET)。3D PET的主要优点是其对较低示踪剂浓度的可检测性。与传统的二维PET相比,3D PET图像具有更好的信噪比。这一点对于研究神经受体配体的分布,如F-18 FDOPA和C-11 YM-01951尤为重要,因为这些配体在大脑中的积聚较低。减少扫描时间对于允许延长扫描时间的患者也很有用。

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