隔日低剂量泼尼松龙对激素依赖型肾病综合征患儿骨龄的影响。

The effect of alternate-day low dose prednisolone on bone age in children with steroid dependent nephrotic syndrome.

作者信息

Bircan Z, Soran M, Yildirim I, Doğan M, Sahin A, Bilici A, Danaci M

机构信息

Dicle University Hospital Pediatrics, Radiology and Statistics, Diyarbakir, Turkey.

出版信息

Int Urol Nephrol. 1997;29(3):357-61. doi: 10.1007/BF02550936.

DOI:10.1007/BF02550936

PMID:9285311

Abstract

Radius, ulna, short bones (RUS), carpal (CARP) bone age (BA), tibial cortico-diaphyseal (C/D) ratio and trabecular aspect were assessed in 19 children with steroid dependent nephrotic syndrome and 15 age matched healthy children. Both RUS and CARP BA were significantly lower than in the controls. Trabecular aspect and tibial C/D ratio did not show any statistical significance. There was a positive correlation between HSDS and RUS BA delay (r = -0.476, p < 0.05); CARP BA delay and RUS BA delay (r = 0.563, p < 0.01) and RUS BA and CARP BA (r = 0.891, p < 0.001). In conclusion, RUS and CARP BA are both retarded and positively correlated in steroid dependent nephrotic children.

摘要

对19名激素依赖型肾病综合征患儿和15名年龄匹配的健康儿童评估了桡骨、尺骨、短骨（RUS）、腕骨（CARP）的骨龄（BA）、胫骨皮质-骨干（C/D）比及小梁形态。RUS和CARP的骨龄均显著低于对照组。小梁形态和胫骨C/D比无统计学差异。激素敏感天数（HSDS）与RUS骨龄延迟呈正相关（r = -0.476，p < 0.05）；CARP骨龄延迟与RUS骨龄延迟呈正相关（r = 0.563，p < 0.01），RUS骨龄与CARP骨龄呈正相关（r = 0.891，p < 0.001）。总之，在激素依赖型肾病患儿中，RUS和CARP的骨龄均延迟且呈正相关。