Kleinman P, Rivelis M, Schneider R, Kaye J J
Radiology. 1977 Dec;125(3):775-80. doi: 10.1148/125.3.775.
The clinical histories and radiographs of 28 patients with ankylosing spondylitis were reviewed. Symptoms developed before the age of 17 in all cases. Juvenile ankylosing spondylitis affected youths in their early teens, who presented most commonly with appendicular joint complaints rather than low back pain. The disease was progressive, with the characteristic changes of ankylosing spondylitis eventually occurring in the spine and sacroiliac joints, frequently accompanied by widespread and severe changes in the appendolar joints. HLA B 27 antigen was present in 8 of the 9 patients tested. Thorough clinical, radiographic, and laboratory examination should prevent confusion with juvenile rheumatoid arthritis.
回顾了28例强直性脊柱炎患者的临床病史和X线片。所有病例症状均在17岁之前出现。青少年强直性脊柱炎影响十几岁的青少年，他们最常见的表现是四肢关节不适而非腰痛。该病呈进行性发展，最终脊柱和骶髂关节出现强直性脊柱炎的特征性改变，常伴有四肢关节广泛而严重的改变。9例接受检测的患者中有8例存在HLA B 27抗原。全面的临床、影像学和实验室检查应可避免与青少年类风湿关节炎混淆。
