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感觉系统中的同步振荡活动:机制新视角

Synchronous oscillatory activity in sensory systems: new vistas on mechanisms.

作者信息

Ritz R, Sejnowski T J

机构信息

Computational Neurobiology Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037-1099, USA.

出版信息

Curr Opin Neurobiol. 1997 Aug;7(4):536-46. doi: 10.1016/s0959-4388(97)80034-7.

DOI:10.1016/s0959-4388(97)80034-7
PMID:9287205
Abstract

The origin and nature, as well as the functional role, of synchronous oscillatory activity in the cortex are among the major unresolved issues in systems neurobiology. Recent advances in understanding the mechanisms underlying oscillations include the description of intrinsically bursting pyramidal cells in striate cortex in vivo and the discovery of inhibitory interneurons that fire spike doublets to induce synchrony. The behavioral consequences of coordinated activity in cortical neurons remain poorly understood.

摘要

皮层同步振荡活动的起源、本质及其功能作用,是系统神经生物学中尚未解决的主要问题。在理解振荡背后机制方面的最新进展包括对活体纹状皮层中具有内在爆发性的锥体细胞的描述,以及发现了通过发放双脉冲来诱导同步性的抑制性中间神经元。皮层神经元协调活动的行为后果仍知之甚少。

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