与雷尼替丁相关的过敏性紫癜。
Henoch-Schonlein purpura associated with ranitidine.
作者信息
Prajapati C, Casson I F
机构信息
Department of Medicine, Broadgreen Hospital, Liverpool, UK.
出版信息
Int J Clin Pract. 1997 Jun;51(4):251.
PMID:9287270
Abstract
Ranitidine is one of the widely prescribed H2 receptor antagonists in the treatment of peptic ulcer. It is well tolerated and has few side-effects. Vasculitic rash occurring in association with ranitidine has been described. We report a case of a 39-year-old man who developed a purpuric rash, polyarthritis, abdominal pain, melaena and impaired renal function characteristic of Henoch-Schonlein purpura, following treatment with ranitidine.
摘要
雷尼替丁是治疗消化性溃疡时广泛使用的H2受体拮抗剂之一。它耐受性良好，副作用较少。曾有与雷尼替丁相关的血管炎性皮疹的报道。我们报告一例39岁男性，在使用雷尼替丁治疗后出现了紫癜性皮疹、多关节炎、腹痛、黑便以及具有过敏性紫癜特征的肾功能损害。
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