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[过敏性紫癜肾炎合并肺肾综合征]

[Shönlein-Henoch nephritis complicated with pulmonary renal syndrome].

作者信息

de la Prada Alvarez F J, Prados Gallardo A M, Tugores Vázquez A, Uriol Rivera M, Saus Sarrias C, Morey Molina A

机构信息

Servicio de Nefrología, Hospital Universitario Son Dureta, Palma de Mallorca, Spain.

出版信息

An Med Interna. 2005 Sep;22(9):441-4.

Abstract

Schönlein-Henoch purpura is a systemic vasculitic disorder involving both arterioles and capillaries. Although it is mainly a disease of early chilhood, it can occur at any age. The disease may be more severe in the few adults who develop this disorder. The clinical manifestations include a classic tetrad: rash, arthralgias, abdominal pain and renal disease. However it may affect almost every other bodily organ such us myocardium, lungs, ureter and nervous system. Pulmonary hemorrhage, a rare complication of Schönlein-Henoch purpura, has been found mainly in adolescents and adults, and it is associated with significant mortality. We present a case of 76-year-old men with Schönlein-Henoch purpura, pulmonary haemorrhage and severe renal involvement. Therapy with intravenous prednisolone resulted in resolution of the pulmonary lesions and renal failure.

摘要

过敏性紫癜是一种累及小动脉和毛细血管的系统性血管炎疾病。尽管它主要是一种儿童早期疾病,但可发生于任何年龄。在少数患此病的成年人中,病情可能更严重。临床表现包括典型的四联征:皮疹、关节痛、腹痛和肾脏疾病。然而,它几乎可能影响身体的其他每个器官,如心肌、肺、输尿管和神经系统。肺出血是过敏性紫癜的一种罕见并发症,主要见于青少年和成年人,且与显著的死亡率相关。我们报告一例76岁男性患有过敏性紫癜、肺出血和严重肾脏受累的病例。静脉注射泼尼松龙治疗使肺部病变和肾衰竭得到缓解。

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