Naito Y, Hirano S, Honjo I, Okazawa H, Ishizu K, Takahashi H, Fujiki N, Shiomi Y, Yonekura Y, Konishi J
Department of Otolaryngology, Kyoto University, Faculty of Medicine, Japan.
Acta Otolaryngol. 1997 Jul;117(4):490-6. doi: 10.3109/00016489709113426.
Changes of regional cerebral blood flow (rCBF) in the auditory cortices induced by sound stimulation were examined in nine postlingually and five prelingually deaf cochlear implant (CI) users by 15O-labeled water Positron Emission Tomography, and the results were compared with those of eight normal volunteers. Speech stimulation caused significantly greater rCBF increase compared with noise stimulation in the auditory association area in normal and postlingually deaf subjects. In prelingually deaf subjects, however, speech activation of the auditory association area was much less than that found in either of the other two groups. Neuronal networks for speech sound processing in the auditory association area in postlingually deaf individuals are thought be similar to those in normal subjects, while those in prelingually deaf patients who received CI after the speech acquisition period may not develop completely.
通过15O标记水正电子发射断层扫描技术，对9名语后聋和5名语前聋的人工耳蜗植入者听觉皮层中由声音刺激引起的局部脑血流量（rCBF）变化进行了检查，并将结果与8名正常志愿者的结果进行了比较。在正常和语后聋受试者中，与噪声刺激相比，言语刺激在听觉联合区引起的rCBF增加显著更大。然而，在语前聋受试者中，听觉联合区的言语激活远低于其他两组中的任何一组。语后聋个体听觉联合区中语音处理的神经网络被认为与正常受试者相似，而在语音习得期后接受人工耳蜗植入的语前聋患者的神经网络可能没有完全发育。
