Rynnel-Dagöö B
Department of Otorhinolaryngology, Huddinge University Hospital, Sweden.
Acta Otolaryngol Suppl. 1997;529:19-21. doi: 10.3109/00016489709124070.
The nasopharynx is a natural reservoir for several bacterial species, including Streptococcus pneumoniae and Haemophilus influenzae. Carriership is a potential mechanism for pathogenicity, since bacteria might invade the Eustachian tube and cause middle ear disease. Whether the pattern of nasopharyngeal colonization is different in infection prone vs healthy children is still a matter of controversy. In several studies it has been shown that H. influenzae is carried significantly more often in otitis-prone children compared with healthy control children. Colonization with H. influenzae in young children may be regarded as a candidate for a microbiological marker for recurrent episodes of acute otitis media.
鼻咽部是多种细菌的天然储存库，包括肺炎链球菌和流感嗜血杆菌。携带状态是一种潜在的致病机制，因为细菌可能侵入咽鼓管并导致中耳疾病。在易感染与健康儿童中，鼻咽部定植模式是否不同仍是一个有争议的问题。多项研究表明，与健康对照儿童相比，易患中耳炎的儿童中流感嗜血杆菌的携带率明显更高。幼儿感染流感嗜血杆菌可被视为急性中耳炎复发的微生物标志物候选因素。
