Koike T, Minakami H, Shiraishi H, Ogawa S, Matsubara S, Honma Y, Sato I
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan.
J Perinat Med. 1997;25(3):295-7.
Hydrops fetalis thought to be due to Ebstein's anomaly was seen at 22 weeks' gestation in one of two fetuses with a monochorionic placenta. Hydrops was treated with maternal digitalization and resolved by the 28th week of gestation. Hydrops did not recur while maternal digitalization continued. A clinical diagnosis of twin-to-twin transfusion syndrome required termination of the pregnancy at 33 weeks of gestation. The twin with Ebstein's anomaly died 22 hours after birth. The other twin survived and was normal at 19 months of age. Thus, administration of digitalis to the mother controlled hydrops fetalis in one fetus, and ultimately led to the survival of the healthy infant.
在一对单绒毛膜胎盘的双胎妊娠中,其中一个胎儿在孕22周时被诊断为胎儿水肿,推测病因是埃布斯坦畸形。胎儿水肿通过母体洋地黄化治疗,在孕28周时消退。在持续母体洋地黄化期间,水肿未复发。双胎输血综合征的临床诊断要求在孕33周时终止妊娠。患有埃布斯坦畸形的胎儿出生后22小时死亡。另一个胎儿存活,19个月大时发育正常。因此,对母亲使用洋地黄控制了一个胎儿的胎儿水肿,并最终使健康婴儿得以存活。