Cesareo R, De Meo M, Agostino A, Reda G
Recenti Prog Med. 1997 Jun;88(6):277-80.
The Authors analyze the use and the efficacy of antithyroidal drugs administered to the patients affected by hyperthyroidism, that must undergo thyroidectomy. The aim is that the patients arrive to the operation in euthyroidism: this is very important to avoid the complications that can occur during or just after the thyroidectomy. They believe that till today the most effective treatment of hyperthyroidism before thyroidectomy is based on the use of thyonamide and iodine. In case of intolerance to these drugs or if it is necessary an emergency thyroidectomy or in case of a low compliance of the patient, there is the possibility to use different therapeutic approaches with beta-blockers or betametasone plus iopanoic acid and propranolol administered together for a few days. As concerning the possible complications that can occur during or after the thyroidectomy, the Authors analyze in particular the thyrotoxicosis and the "hungry bone" syndrome.
作者分析了给予必须接受甲状腺切除术的甲状腺功能亢进症患者抗甲状腺药物的使用情况及疗效。目的是使患者在甲状腺功能正常的状态下接受手术：这对于避免甲状腺切除术中或术后可能出现的并发症非常重要。他们认为，迄今为止，甲状腺切除术前治疗甲状腺功能亢进症最有效的方法是使用硫酰胺类药物和碘。如果对这些药物不耐受，或者有必要进行急诊甲状腺切除术，或者患者依从性差，则有可能采用不同的治疗方法，如使用β受体阻滞剂，或使用倍他米松加碘番酸和普萘洛尔联合使用几天。关于甲状腺切除术中或术后可能出现的并发症，作者特别分析了甲状腺毒症和“饥饿骨”综合征。
