Mariutin P V, Uchvatkin V G, Rybin E P, Grakh S I, Sokirskiĭ E K
Anesteziol Reanimatol. 1997 May-Jun(3):14-8.
A third-generation cephalosporin, Ceftriaxone, was used in intensive care of patients subjected to elective and urgent surgery in the Regional Clinical Hospital, St. Petersburg. A total of 105 patients were divided in 4 groups: 1) a course of ceftriaxone in combination with aminoglycosides started before the intervention; 2) the same, with the disease course complicated by peritonitis; 3) patients with neurosurgical diseases and brain injuries complicated by secondary meningoencephalitis; and 4) abdominal surgical patients in whom the severity of illness was determined by the abdominal process of different localization. The treatment included general and local use of ceftriaxone under ultrasonic control. The results indicate that ceftriaxone is a broad-spectrum drug effective in the treatment of nosocomial infections and neuroinfections; it can be applied locally and is economic.
第三代头孢菌素头孢曲松用于圣彼得堡地区临床医院接受择期和急诊手术患者的重症监护。总共105例患者被分为4组：1）干预前开始使用头孢曲松联合氨基糖苷类药物的疗程；2）病情过程合并腹膜炎的相同情况；3）患有神经外科疾病和脑损伤并继发脑膜脑炎的患者；4）腹部手术患者，其疾病严重程度由不同部位的腹部病变决定。治疗包括在超声控制下全身和局部使用头孢曲松。结果表明，头孢曲松是一种广谱药物，对治疗医院感染和神经感染有效；它可以局部应用且经济实惠。
