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[氧氟沙星在外科化脓性炎症并发症治疗中的应用]

[Use of ofloxacin in the treatment of suppurative-inflammatory complications in surgery].

作者信息

Bogomolova N S, Bol'shakov L V, Vinogradova L N, Sorokina V I, Oreshkina T D, Tret'iakova E S

出版信息

Anesteziol Reanimatol. 1997 May-Jun(3):18-20.

PMID:9289979
Abstract

Analysis of ofloxacin use in clinical surgery over the latest decade showed that despite its wide clinical application for the prevention and therapy of postoperative complications, this drug remains highly active for the majority of micro-organisms. Hence, a wide spectrum, high bactericidal activity of the drug, optimal pharmacokinetics, and a high bio-availability (95-100%) still recommend ofloxacin, a highly effective agent for the treatment of infectious complications of surgery.

摘要

对过去十年临床外科中氧氟沙星使用情况的分析表明,尽管其在预防和治疗术后并发症方面有广泛的临床应用,但该药物对大多数微生物仍具有高度活性。因此,该药物的广谱、高杀菌活性、最佳药代动力学以及高生物利用度(95 - 100%)仍然使氧氟沙星成为治疗外科感染性并发症的高效药物。 (注:原文中Analysis of ofloxacin use in clinical surgery over the latest decade showed that despite its wide clinical application for the prevention and therapy of postoperative complications, this drug remains highly active for the majority of micro-organisms. Hence, a wide spectrum, high bactericidal activity of the drug, optimal pharmacokinetics, and a high bio-availability (95-100%) still recommend ofloxacin, a highly effective agent for the treatment of infectious complications of surgery.中Analysis of ofloxacin use in clinical surgery over the latest decade showed that despite its wide clinical application for the prevention and therapy of postoperative complications, this drug remains highly active for the majority of micro-organisms. Hence, a wide spectrum, high bactericidal activity of the drug, optimal pharmacokinetics, and a high bio-availability (95-100%) still recommend ofloxacin, a highly effective agent for the treatment of infectious complications of surgery.中Analysis of ofloxacin use in clinical surgery over the latest decade showed that despite its wide clinical application for the prevention and therapy of postoperative complications, this drug remains highly active for the majority of micro-organisms. Hence, a wide spectrum, high bactericidal activity of the drug, optimal pharmacokinetics, and a high bio-availability (95-100%) still recommend ofloxacin, a highly effective agent for the treatment of infectious complications of surgery.存在重复表述,已按正确内容翻译)

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