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美国成年人的人类免疫缺陷病毒RNA水平:基于种族和族裔的比较。

Human immunodeficiency virus RNA levels in US adults: a comparison based upon race and ethnicity.

作者信息

Brown A E, Malone J D, Zhou S Y, Lane J R, Hawkes C A

机构信息

Combined Military Diagnostic Retrovirology Service, Walter Reed Army Institute of Research, Henry M. Jackson Foundation, and SRA Technologies, Rockville, Maryland, USA.

出版信息

J Infect Dis. 1997 Sep;176(3):794-7. doi: 10.1086/517304.

DOI:10.1086/517304
PMID:9291336
Abstract

Volunteers in a natural history study of human immunodeficiency virus type 1 (HIV-1) at two military medical centers were studied to determine whether plasma HIV-1 RNA levels differ among racial and ethnic groups of US adults infected with HIV-1. Cross-sectional analyses of plasma HIV-1 RNA and CD4 cell counts were done using demographic and clinical data collected during study visits. Age, gender, CD4 cell count, seroconversion status, and use of antiretroviral therapy were studied in 545 military members (46% white, 49% black, and 6% Hispanic). No association was found between HIV-1 RNA levels and race or ethnicity among infected adults for whom access to care and socioeconomic status were not confounding factors.

摘要

在两个军事医疗中心进行的一项关于1型人类免疫缺陷病毒(HIV-1)的自然史研究中,对志愿者进行了研究,以确定感染HIV-1的美国成年种族和族裔群体之间的血浆HIV-1 RNA水平是否存在差异。利用研究访视期间收集的人口统计学和临床数据,对血浆HIV-1 RNA和CD4细胞计数进行了横断面分析。对545名军人(46%为白人,49%为黑人,6%为西班牙裔)的年龄、性别、CD4细胞计数、血清转化状态和抗逆转录病毒治疗的使用情况进行了研究。在获得医疗服务和社会经济地位不是混杂因素的感染成年人中,未发现HIV-1 RNA水平与种族或族裔之间存在关联。

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