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接受医疗护理时以及HIV-1感染后随访期间CD4 T细胞计数和病毒载量的种族/民族差异。

Racial/ethnic differences in CD4 T cell count and viral load at presentation for medical care and in follow-up after HIV-1 infection.

作者信息

Swindells Susan, Cobos Daniel G, Lee Nancy, Lien Elizabeth A, Fitzgerald Ann P, Pauls Jennifer S, Anderson James R

机构信息

Department of Internal Medicine, Universitsity of Nebraska Medical Center, Omaha, NE, USA.

出版信息

AIDS. 2002 Sep 6;16(13):1832-4. doi: 10.1097/00002030-200209060-00020.

DOI:10.1097/00002030-200209060-00020
PMID:12218399
Abstract

The baseline characteristics of antiretroviral-naive patients were compared by ethnic/racial groups. First CD4 T cell counts were lower for Latino (P = 0.0004) and black patients (P = 0.10) when compared with white patients. First HIV-1-RNA levels were higher in Latino patients (P = 0.08), who were also more likely to present with major opportunistic infections (P < 0.004). Once in care, changes in CD4 T cell counts and viral loads over time did not differ significantly between groups.

摘要

对抗逆转录病毒治疗初治患者的基线特征按种族/族裔群体进行了比较。与白人患者相比,拉丁裔患者(P = 0.0004)和黑人患者(P = 0.10)的首次CD4 T细胞计数较低。拉丁裔患者的首次HIV-1-RNA水平较高(P = 0.08),他们也更有可能出现严重机会性感染(P < 0.004)。一旦接受治疗,各组之间CD4 T细胞计数和病毒载量随时间的变化没有显著差异。

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