食管癌：治疗结果
Carcinoma of the esophagus: results of treatment.
作者信息
van Andel J G, Dees J, Dijkhuis C M, Fokkens W, van Houten H, de Jong P C, van Woerkom-Eykenboom W M
出版信息
Ann Surg. 1979 Dec;190(6):684-9. doi: 10.1097/00000658-197912000-00002.
The treatment results of the Rotterdam working group on esophageal cancer during the period January 1970-January 1978 were assessed. A total number of 328 patients were treated: 230 males and 98 females. Of the 133 patients eligible for a combined treatment modality i.e. preoperative radiotherapy and surgery, 52 showed irresectable or metastatic disease during operation. The five year actuarial survival rate of the 81 patients, in whom curative surgical resection of the tumor was performed, amounted to 21%. Females fared better than males, the five year survivals being 42% and 12% respectively. This female preponderance in survival is partly explained by the considerable postoperative mortality of the male patients: 28% vs 7.4% in females. Patients who received only radiation therapy, whether curative or palliative, had a very bad prognosis. It is concluded that preoperative irradiation followed by surgical removal of the tumor should be performed in all operable-curable patients.
对鹿特丹食管癌工作组在1970年1月至1978年1月期间的治疗结果进行了评估。总共治疗了328例患者，其中男性230例，女性98例。在133例适合联合治疗方式（即术前放疗和手术）的患者中，52例在手术期间显示出不可切除或转移性疾病。81例接受了肿瘤根治性手术切除的患者的五年精算生存率为21%。女性的情况优于男性，五年生存率分别为42%和12%。女性在生存方面的优势部分归因于男性患者相当高的术后死亡率：女性为7.4%，男性为28%。仅接受放射治疗的患者，无论治疗是根治性还是姑息性的，预后都非常差。得出的结论是，所有可手术治愈的患者都应先进行术前放疗，然后手术切除肿瘤。
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