Schuchmann G F, Heydorn W H, Hall R V, Carter S C, Gillespie J T, Grishkin B A, James E C
J Thorac Cardiovasc Surg. 1980 Jan;79(1):67-73.
Two hundred fourteen patients underwent treatment for carcinoma of the esophagus between January, 1950, and July, 1978, with an over-all 5 year survival rate of 1.9%. Forty-six patients (21.5% of series) underwent esophageal resection with either esophagogastrostomy (37 patients) or colon interposition (nine patients). The operative mortality rate was 18.9% for the esophagogastrectomy group and 33% for the colon interposition patients. "Curative" resections resulted in a 14.3% 5 year survival rate. One hundred twenty-seven patients (59.3% of series) were treated by irradiation therapy, with a mean survival time of 9.6 months for patients receiving "curative" dosage (over 4,500 rads). There were no 5 year survivors in this group. Palliative procedures, such as feeding gastrostomy and palliative (less than 4,500 rads) irradiation therapy, contributed little to patient comfort or survival. We favor a palliative approach to the treatment of esophageal carcinoma and believe that, when possible, esophageal resection with esophagogastrostomy is the preferable form of therapy and offers an occasional cure.
1950年1月至1978年7月期间，214例食管癌患者接受了治疗，总体5年生存率为1.9%。46例患者（占该系列的21.5%）接受了食管切除术，其中37例行食管胃吻合术，9例行结肠代食管术。食管胃切除术组的手术死亡率为18.9%，结肠代食管术患者的手术死亡率为33%。“根治性”切除术后5年生存率为14.3%。127例患者（占该系列的59.3%）接受了放射治疗，接受“根治性”剂量（超过4500拉德）的患者平均生存时间为9.6个月。该组无5年生存者。姑息性手术，如胃造瘘术和姑息性（小于4500拉德）放射治疗，对患者的舒适度或生存率贡献不大。我们倾向于采用姑息性方法治疗食管癌，并认为，在可能的情况下，食管胃吻合术式的食管切除术是更可取的治疗方式，偶尔可实现治愈。
